Article
Prevalence and molecular basis of glucose-6-phosphate dehydrogenase deficiency in Afghan populations: implications for treatment policy in the region.
Malaria journal - 8 Jul 2013
Leslie Toby, Moiz Bushra, Mohammad Nader, Amanzai Omar, Ur Rasheed Haroon, Jan Sakhi, Siddiqi Abdul M, Nasir Amna, Beg Mohammad A, Vink Martijn
Abstract excerpt
BACKGROUND: Glucose-6-phosphate dehydrogenase deficiency (G6PD), an x-linked inherited enzymopathy, is a barrier to malaria control because primaquine cannot be readily applied for radical cure in individuals with the condition. In endemic areas, including in Afghanistan, the G6PD status of vivax patients is not routinely determined so the drug is rarely, if ever, prescribed even though it is included as a...
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