Article
The G6PD flow-cytometric assay is a reliable tool for diagnosis of G6PD deficiency in women and anaemic subjects.
Scientific reports - 29 Aug 2017
Bancone Germana, Kalnoky Michael, Chu Cindy S, Chowwiwat Nongnud, Kahn Maria, Malleret Benoit, Wilaisrisak Pornpimon, Rénia Laurent, Domingo Gonzalo J, Nosten Francois
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) activity is essential for redox equilibrium of red blood cells (RBCs) and, when compromised, the RBCs are more susceptible to haemolysis. 8-aminoquinolines (primaquine and tafenoquine) are used for the radical curative treatment of Plasmodium vivax malaria and can cause haemolysis in G6PD deficient subjects. Haemolytic risk is dependent on treatment dose and patient G6PD...
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