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Article

Genotypes and phenotypes of G6PD deficiency among Indonesian females across diagnostic thresholds of G6PD activity guiding safe primaquine therapy of latent malaria.

PLoS neglected tropical diseases - 1 Jul 2021

Satyagraha Ari Winasti, Sadhewa Arkasha, Panggalo Lydia Visita, Subekti Decy, Elyazar Iqbal, Soebianto Saraswati, Mahpud Nunung, Harahap Alida Rosita, Baird J Kevin

Abstract excerpt

BACKGROUND: Plasmodium vivax occurs as a latent infection of liver and a patent infection of red blood cells. Radical cure requires both blood schizontocidal and hypnozoitocidal chemotherapies. The hypnozoitocidal therapies available are primaquine and tafenoquine, 8-aminoquinoline drugs that can provoke threatening acute hemolytic anemia in patients having an X-linked G6PD-deficiency. Heterozygous females may...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34270547
DOI: 10.1371/journal.pntd.0009610
PMCID: PMC8318249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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