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Article

Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study.

Hepatology (Baltimore, Md.) - 1 Jan 2016

Goffredo Martina, Caprio Sonia, Feldstein Ariel E, D'Adamo Ebe, Shaw Melissa M, Pierpont Bridget, Savoye Mary, Zhao Hongyu, Bale Allen E, Santoro Nicola

Abstract excerpt

UNLABELLED: We assessed the association between the single-nucleotide polymorphism (SNP) rs58542926 in the transmembrane 6 superfamily member 2 (TM6SF2) gene and fatty liver disease in obese youth. We genotyped the TM6SF2 rs58542926 SNP in a multiethnic cohort of 957 obese children and adolescents (42% Caucasians, 28% African Americans, 30% Hispanics). All underwent an oral glucose tolerance test, a liver panel,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26457389
DOI: 10.1002/hep.28283
PMCID: PMC4688225

Genes

GCKR
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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