Article
Prediction of TERTp-mutation status in IDH-wildtype high-grade gliomas using pre-treatment dynamic [18F]FET PET radiomics.
European journal of nuclear medicine and molecular imaging - 1 Dec 2021
Li Zhicong, Kaiser Lena, Holzgreve Adrien, Ruf Viktoria C, Suchorska Bogdana, Wenter Vera, Quach Stefanie, Herms Jochen, Bartenstein Peter, Tonn Jörg-Christian, Unterrainer Marcus, Albert Nathalie L
Abstract excerpt
PURPOSE: To evaluate radiomic features extracted from standard static images (20-40 min p.i.), early summation images (5-15 min p.i.), and dynamic [18F]FET PET images for the prediction of TERTp-mutation status in patients with IDH-wildtype high-grade glioma. METHODS: A total of 159 patients (median age 60.2 years, range 19-82 years) with newly diagnosed IDH-wildtype diffuse astrocytic glioma (WHO grade III or...
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