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Article

Two-Stage Training Framework Using Multicontrast MRI Radiomics for IDH Mutation Status Prediction in Glioma.

Radiology. Artificial intelligence - 1 Jul 2024

Truong Nghi C D, Bangalore Yogananda Chandan Ganesh, Wagner Benjamin C, Holcomb James M, Reddy Divya, Saadat Niloufar, Hatanpaa Kimmo J, Patel Toral R, Fei Baowei, Lee Matthew D, Jain Rajan, Bruce Richard J, Pinho Marco C, Madhuranthakam Ananth J, Maldjian Joseph A

Abstract excerpt

Purpose To develop a radiomics framework for preoperative MRI-based prediction of isocitrate dehydrogenase (IDH) mutation status, a crucial glioma prognostic indicator. Materials and Methods Radiomics features (shape, first-order statistics, and texture) were extracted from the whole tumor or the combination of nonenhancing, necrosis, and edema regions. Segmentation masks were obtained via the federated tumor...

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Identifiers

PMID: 38775670
DOI: 10.1148/ryai.230218
PMCID: PMC11294953

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