Article
Voxel-based 18F-FET PET segmentation and automatic clustering of tumor voxels: A significant association with IDH1 mutation status and survival in patients with gliomas.
PloS one - 1 Jan 2018
Blanc-Durand Paul, Van Der Gucht Axel, Verger Antoine, Langen Karl-Josef, Dunet Vincent, Bloch Jocelyne, Brouland Jean-Philippe, Nicod-Lalonde Marie, Schaefer Niklaus, Prior John O
Abstract excerpt
INTRODUCTION: Aim was to develop a full automatic clustering approach of the time-activity curves (TAC) from dynamic 18F-FET PET and evaluate its association with IDH1 mutation status and survival in patients with gliomas. METHODS: Thirty-seven patients (mean age: 45±13 y) with newly diagnosed gliomas and dynamic 18F-FET PET before any histopathologic investigation or treatment were retrospectively included. Each...
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