Article
Feline adipose-derived mesenchymal stem cells induce effector phenotype and enhance cytolytic function of CD8+ T cells.
Stem cell research & therapy - 6 Sept 2021
Taechangam Nopmanee, Walker Naomi J, Borjesson Dori L
Abstract excerpt
BACKGROUND: Feline adipose-derived mesenchymal stem cells (ASCs) engage with a variety of immune cells and have been used in several clinical trials for the treatment of inflammatory and immune-dysregulated diseases in cats, but the impact they exert on the functional characteristics on T cells, particularly CD8+ T cells, remains to be elucidated. METHODS: Modified mixed leukocyte reaction was performed between...
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