Article
Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.
Blood advances - 12 Oct 2021
de Groen Ruben A L, van Eijk Ronald, Böhringer Stefan, van Wezel Tom, Raghoo Richard, Ruano Dina, Jansen Patty M, Briaire-de Bruijn Inge, de Groot Fleur A, Kleiverda Karin, Te Boome Liane, Terpstra Valeska, Levenga Henriette, Nicolae Alina, Posthuma Eduardus F M, Focke-Snieders Isabelle, Hardi Lizan, den Hartog Wietske C E, Bohmer Lara H, Hogendoorn Pancras C W, van den Berg Anke, Diepstra Arjan, Nijland Marcel, Lugtenburg Pieternella J, Kersten Marie José, Pals Steven T, Veelken Hendrik, Bovée Judith V M G, Cleven Arjen H G, Vermaat Joost S P
Abstract excerpt
Primary bone diffuse large B-cell lymphoma (PB-DLBCL) is a rare extranodal lymphoma subtype. This retrospective study elucidates the currently unknown genetic background of a large clinically well-annotated cohort of DLBCL with osseous localizations (O-DLBCL), including PB-DLBCL. A total of 103 patients with O-DLBCL were included and compared with 63 (extra)nodal non-osseous (NO)-DLBCLs with germinal center...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.