Article
Effects of Pegylated Interferon Alpha and Ribavirin (pegIFN-α/RBV) Therapeutic Approach on Regulatory T Cells in HCV-Monoinfected and HCV/HIV-Coinfected Patients.
Viruses - 25 Jul 2021
Grubczak Kamil, Grzeszczuk Anna, Groth Monika, Hryniewicz Anna, Kretowska-Grunwald Anna, Flisiak Robert, Moniuszko Marcin
Abstract excerpt
Approximately 25% of HIV-infected patients are co-infected with HCV. Notably, the burden of HCV infection (e.g., viral persistence, viral load, or HCV-related liver symptoms) is more pronounced in the presence of HIV co-infection. However, to date, the underlying immune mechanisms accounting for accelerated disease progression in HIV/HCV-coinfected individuals have not been described in sufficient detail. We...
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