Article
Hepatic compartmentalization of exhausted and regulatory cells in HIV/HCV-coinfected patients.
Journal of viral hepatitis - 1 Mar 2015
Barrett L, Trehanpati N, Poonia S, Daigh L, Sarin S Kumar, Masur H, Kottilil S
Abstract excerpt
Accelerated intrahepatic hepatitis C virus (HCV) pathogenesis is likely the result of dysregulation within both the innate and adaptive immune compartments, but the exact contribution of peripheral blood and liver lymphocyte subsets remains unclear. Prolonged activation and expansion of immunoregulatory cells have been thought to play a role. We determined immune cell subset frequency in contemporaneous liver and...
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