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Assessing donor-to-donor variability in human intestinal organoid cultures

26 Aug 2021

Abstract excerpt

Donor-to-donor variability in primary human organoid cultures has not been well characterized. As these cultures contain multiple cell types, there is greater concern that variability could lead to increased noise. In this work we investigated donor-to-donor variability in human gut adult stem cell (ASC) organoids. We examined intestinal developmental pathways during culture differentiation in ileum- and...

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PMID: 34450035
DOI: 10.1016/j.stemcr.2021.07.016

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