Article
TCGA molecular subgroups of endometrial carcinoma in ovarian endometrioid carcinoma: A quantitative systematic review.
Gynecologic oncology - 1 Nov 2021
D'Alessandris Nicoletta, Travaglino Antonio, Santoro Angela, Arciuolo Damiano, Scaglione Giulia, Raffone Antonio, Inzani Frediano, Zannoni Gian Franco
Abstract excerpt
BACKGROUND: Ovarian endometrioid carcinoma (OEC) shares morphological and molecular features with endometrial endometrioid carcinoma (EEC). Several studies assessed the four TCGA groups of EEC, i.e. POLE-mutated (POLEmut), mismatch repair-deficient (MMRd), no specific molecular profile (NSMP) and p53-abnormal (p53abn), in OEC; however, it is unclear whether the TCGA groups have the same distribution and...
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