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The Changes in the p53 Protein across the Animal Kingdom Point to Its Involvement in Longevity

7 Aug 2021

Abstract excerpt

Recently, the quest for the mythical fountain of youth has produced extensive research programs that aim to extend the healthy lifespan of humans. Despite advances in our understanding of the aging process, the surprisingly extended lifespan and cancer resistance of some animal species remain unexplained. The p53 protein plays a crucial role in tumor suppression, tissue homeostasis, and aging. Long-lived,...

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PMID: 34445220
DOI: 10.3390/ijms22168512

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