Children with Down syndrome: association of Bcl-I polymorphism of nuclear receptor subfamily 3 group C member 1 gene with obesity.

doi:10.1038/s41390-021-01711-3

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Article

Children with Down syndrome: association of Bcl-I polymorphism of nuclear receptor subfamily 3 group C member 1 gene with obesity.

Pediatric research - 1 Jul 2022

Abo El-Fotoh Wafaa Moustafa M, Bahbah Hebatallah Mohammed Nasser, Elaithy Manal Abd El-Monem, Ahmed Rana Khairy Rashad, Bayomy Noha Rabie

Abstract excerpt

BACKROUND: This study aimed to assess the possible association between rs41423247 (Bcl-I) polymorphism in the gene for the human glucocorticoid receptor (GR) called Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1) with obesity in Egyptian children with and without Down syndrome. METHODS: The Bcl-I polymorphism was assessed, using real-time PCR, in 300 children divided into four groups: Down-obese, Down-non...

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PMID: 34433889
DOI: 10.1038/s41390-021-01711-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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