Variants in proinflammatory genes IL1RL1, IL1B and IRF4 are associated with overweight in a pediatric Brazilian population.

doi:10.1016/j.gene.2022.146478

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Article

Variants in proinflammatory genes IL1RL1, IL1B and IRF4 are associated with overweight in a pediatric Brazilian population.

Gene - 20 Jun 2022

Melo Ana Paula Castro, Teixeira Helena Mariana Pitangueira, Coelho Raisa Santos, De Jesus Talita Dos Santos, Queiroz Gerson Almeida, Silva Hatilla Dos Santos, De Almeida Yasmim Cristina Ferreira, Alcantara-Neves Neuza Maria, De Matos Sheila Maria Alvim, D'innocenzo Silvana, Silva Rita De Cassia Ribeiro, Lima Barreto Maurício, Costa Ryan Dos Santos, Pinto Laise Cedraz, Figueiredo Camila Alexandrina

Abstract excerpt

BACKGROUND: Obesity is a chronic complex disease with great prevalence for children all over the world. Characterized for low-grade inflammation associated with several comorbidities such as resistance and type 2 diabetes mellitus (T2DM). OBJECTIVES: To investigate whether genetic variants in IL10, IL1RL1, IL1B, IRF4, TNF, IL6, and IL33 genes are associated with being overweight in children. METHODS: We performed...

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PMID: 35390444
DOI: 10.1016/j.gene.2022.146478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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