Association between FTO gene polymorphism and obesity in down syndrome children.

doi:10.1007/s00431-024-05909-5

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Article

Association between FTO gene polymorphism and obesity in down syndrome children.

European journal of pediatrics - 21 Dec 2024

Mourad Shereen A, El-Farahaty Reham M, Atwa Mohamed A, Yahia Sohier, El-Gilany Abdel-Hady, Elzeiny Ahmed A, Elhennawy Eman S

Abstract excerpt

Children with Down syndrome (DS) have a higher incidence of overweight and obesity compared to typically developing peers. The fat mass and obesity-associated gene (FTO) is one of the early identified genes linked to obesity in various populations. To date, the FTO rs17817449 gene polymorphism has not been investigated in overweight/obese-DS (ODS) individuals. The current study aimed to explore the potential...

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PMID: 39706986
DOI: 10.1007/s00431-024-05909-5
PMCID: PMC11662052

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