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Characterization of an operon required for growth on cellobiose in Clostridioides difficile

19 Aug 2021

Abstract excerpt

Cellobiose metabolism is linked to the virulence properties in numerous bacterial pathogens. Here, we characterized a putative cellobiose PTS operon of Clostridiodes difficile to investigate the role of cellobiose metabolism in C. difficile pathogenesis. Our gene knockout experiments demonstrated that the putative cellobiose operon enables uptake of cellobiose into C. difficile and allows growth when cellobiose...

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PMID: 34410904
DOI: 10.1099/mic.0.001079

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