Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accessory Gene Regulator-1 Locus Is Essential for Virulence and Pathogenesis of Clostridium difficile

17 Aug 2016

Abstract excerpt

UNLABELLED: Clostridium difficile infection (CDI) is responsible for most of the definable cases of antibiotic- and hospital-associated diarrhea worldwide and is a frequent cause of morbidity and mortality in older patients. C. difficile, a multidrug-resistant anaerobic pathogen, causes disease by producing toxins A and B, which are controlled by an accessory gene regulator (Agr) quorum signaling system. Some C....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacillus and Francisella bacterial research
Share to Clostridium difficile and Clostridium perfringens research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27531912
DOI: 10.1128/mbio.01237-16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accessory Gene Regulator-1 Locus Is Essential for Virulence and Pathogenesis of Clostridium difficilePMID 27531912Read ↗

Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production.Semantic proximity Read ↗

Pathogenicity and virulence of Clostridioides difficileSemantic proximity Read ↗

Clostridium difficile infectionSemantic proximity Read ↗

Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile VirulenceSemantic proximity Read ↗

Targeting agr- and agr-Like Quorum Sensing Systems for Development of Common Therapeutics to Treat Multiple Gram-Positive Bacterial InfectionsSemantic proximity Read ↗

The Agr-Like Quorum-Sensing System Regulates Sporulation and Production of Enterotoxin and Beta2 Toxin by Clostridium perfringens Type A Non-Food-Borne Human Gastrointestinal Disease Strain F5603Semantic proximity Read ↗

<i>Clostridium difficile</i>virulence factors: Insights into an anaerobic spore-forming pathogenSemantic proximity Read ↗

Toxin Synthesis by Clostridium difficile Is Regulated through Quorum SignalingSemantic proximity Read ↗

<i>Clostridioides difficile</i> exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiotaSemantic proximity Read ↗

Virulence Gene Regulation by the <i>agr</i> System in <i>Clostridium perfringens</i>Semantic proximity Read ↗

A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota DiversitySemantic proximity Read ↗

Genomic and phenotypic studies among <i>Clostridioides difficile</i> isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrheaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.