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Article

No Association of filaggrin copy number variation and atopic dermatitis risk in White and Black Americans.

Experimental dermatology - 1 Feb 2022

Fulton Rachel L, Margolis David J, Sockler Patrick G, Mitra Nandita, Wong Xuan Fei Colin Cornelius, Common John E

Abstract excerpt

Atopic dermatitis (AD) is a chronic, inflammatory skin condition with a multifactorial pathophysiology. The filaggrin gene (FLG) has particularly been implicated given loss of function (LoF) mutations in this gene lead to skin barrier dysfunction and such mutations can increase a patient's likelihood of developing AD. FLG has intragenic copy number variation (CNV), which impacts the total amount of filaggrin...

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Identifiers

PMID: 34407261
DOI: 10.1111/exd.14449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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