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Article

Circulating Pro-Inflammatory Exosomes Worsen Stroke Outcomes in Aging

17 Aug 2021

Abstract excerpt

Rationale: The systemic inflammatory milieu plays an important role in the age-related decline in functional integrity, but its contribution to age-related disease (eg, stroke) remains largely unknown. Objective: To determine the role of systemic inflammatory milieu in ischemic stroke. Methods and Results: Here, we report that systemic administration of serum exosomes from young rats into aged ischemic rats...

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PMID: 34399581
DOI: 10.1161/circresaha.121.318897

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