Article
Endothelial-derived exosomes demonstrate a link between endothelial innate inflammation and brain dysfunction and injury in aging
2019-06-21
Abstract excerpt
<h4>ABSTRACT</h4> We test the hypothesis that endothelial cells take on an inflammatory phenotype in functionally intact human subjects with radiographic evidence of white matter injury. Markers within all three complement effector pathways and regulatory proteins were quantified from endothelial-derived exosomes (EDE) of subjects (age 70-82) with (n=11) and without (n=16) evidence of white matter hyperintensity...
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Identifiers and source
- Literature Corpus work
- 6f3c863a-b5e9-5ea5-ba60-2c46d32e23f7
- DOI
- 10.1101/670083