Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host Genetic Risk Factors for Chlamydia trachomatis-Related Infertility in Women.

The Journal of infectious diseases - 16 Aug 2021

Zheng Xiaojing, Zhong Wujuan, O'Connell Catherine M, Liu Yutong, Haggerty Catherine L, Geisler William M, Anyalechi Gloria E, Kirkcaldy Robert D, Wiesenfeld Harold C, Hillier Sharon L, Steinkampf Michael P, Hammond Karen R, Fine Jason, Li Yun, Darville Toni

Abstract excerpt

BACKGROUND: Chlamydia trachomatis (Ct) infection ascending to the upper genital tract can cause infertility. Direct association of genetic variants as contributors is challenging because infertility may not be diagnosed until years after infection. Investigating the intermediate trait of ascension bridges this gap. METHODS: We identified infertility genome-wide association study (GWAS) loci using deoxyribonucleic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlamydia Infections
Share to Chlamydia trachomatis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Host Microbial Interactions

Share to Infertility

Share to Infertility, Female

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 34396400
DOI: 10.1093/infdis/jiab149
PMCID: PMC8365119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host Genetic Risk Factors for Chlamydia trachomatis-Related Infertility in Women.PMID 34396400Read ↗

Human and Pathogen Factors Associated with Chlamydia trachomatis-Related Infertility in WomenSemantic proximity Read ↗

Chlamydia trachomatis: From Urogenital Infections to the Pathway of InfertilitySemantic proximity Read ↗

Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan.Semantic proximity Read ↗

Pathways-wide genetic risks in Chlamydial infections overlap between tissue tropisms: A genome-wide association scanSemantic proximity Read ↗

Causal Relationship Between Antibody‐Mediated Immune Responses of Chlamydia trachomatis Infection and Reproductive Tract Complications: A Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

Genetic susceptibility loci for Chlamydia trachomatis endometrial infection influence expression of genes involved in T cell function, tryptophan metabolism and epithelial integrity.Semantic proximity Read ↗

Whole-Exome Sequencing to Identify Novel Biological Pathways Associated With Infertility After Pelvic Inflammatory DiseaseSemantic proximity Read ↗

Infertility Affects 1 in 6 People GloballySemantic proximity Read ↗

Associations between cytokines and the risk of female and male infertility: A two-sample Mendelian randomization analysis.Semantic proximity Read ↗

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study.Semantic proximity Read ↗

Chlamydia trachomatis infections and subfertility: opportunities to translate host pathogen genomic data into public health.Semantic proximity Read ↗

Association of CCR5, TLR2, TLR4 and MBL genetic variations with genital tract infections and tubal factor infertility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.