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Early and late stage MPN patients show distinct gene expression profiles in CD34+ cells

14 Aug 2021

Abstract excerpt

Abstract Myeloproliferative neoplasms (MPN), comprising essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF), are hematological disorders of the myeloid lineage characterized by hyperproliferation of mature blood cells. The prediction of the clinical course and progression remains difficult and new therapeutic modalities are required. We conducted a CD34+ gene expression study...

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PMID: 34390367
DOI: 10.1007/s00277-021-04615-8

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