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Article

Transcriptomic comparison of bone marrow CD34 + cells and peripheral blood neutrophils from ET patients with JAK2 or CALR mutations.

BMC genomic data - 7 Aug 2023

Guijarro-Hernández Ana, Vizmanos José Luis

Abstract excerpt

BACKGROUND: Essential thrombocythemia (ET) is one of the most common types of Ph-negative myeloproliferative neoplasms, an infrequent group of blood cancers that arise from a CD34 + hematopoietic stem cell (HSC) in the bone marrow (BM) primarily due to driver mutations in JAK2, CALR or MPL. These aberrations result in an overproduction of mature myeloid cells in peripheral blood (PB). To date, no targeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37550636
DOI: 10.1186/s12863-023-01142-5
PMCID: PMC10408115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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