Article

Platelet transcriptome yields progressive markers in chronic myeloproliferative neoplasms and identifies putative targets of therapy

2021-03-12

Abstract excerpt

Predicting disease progression remains a particularly challenging endeavor in chronic degenerative disorders and cancer, thus limiting early detection, risk stratification, and preventive interventions. Here, profiling the spectrum of chronic myeloproliferative neoplasms (MPNs) as a model, we identify the blood platelet transcriptome as a proxy for highly sensitive progression biomarkers that also enables predicti...

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Literature Corpus work: 5fdb0eb7-6b90-5f0c-966e-5d90c5dfd084
DOI: 10.1101/2021.03.12.435190

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