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Article

Tyrosine phosphorylation of lamin A by Src promotes disassembly of nuclear lamina in interphase.

Life science alliance - 1 Oct 2021

Chu Ching-Tung, Chen Yi-Hsuan, Chiu Wen-Tai, Chen Hong-Chen

Abstract excerpt

Lamins form the nuclear lamina, which is important for nuclear structure and activity. Although posttranslational modifications, in particular serine phosphorylation, have been shown to be important for structural properties and functions of lamins, little is known about the role of tyrosine phosphorylation in this regard. In this study, we found that the constitutively active Src Y527F mutant caused the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34385357
DOI: 10.26508/lsa.202101120
PMCID: PMC8362257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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