Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SLUG‐related partial epithelial‐to‐mesenchymal transition is a transcriptomic prognosticator of head and neck cancer survival

12 Aug 2021

Abstract excerpt

Partial epithelial‐to‐mesenchymal transition (pEMT) contributes to cellular heterogeneity that is associated with nodal metastases and unfavorable clinical parameters in head and neck squamous cell carcinomas (HNSCCs). We developed a single‐cell RNA sequencing signature‐based pEMT quantification through cell type‐dependent deconvolution of bulk RNA sequencing and microarray data combined with single‐sample...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to Metastasis and carcinoma case studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34382739
DOI: 10.1002/1878-0261.13075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SLUG‐related partial epithelial‐to‐mesenchymal transition is a transcriptomic prognosticator of head and neck cancer survivalPMID 34382739Read ↗

Partial epithelial-to-mesenchymal transition is prognostic and associates with Slug in head and neck cancerSemantic proximity Read ↗

Integrative Single-Cell and Bulk Transcriptomes Analyses Identify Intrinsic HNSCC Subtypes with Distinct Prognoses and Therapeutic VulnerabilitiesSemantic proximity Read ↗

A Novel Four-CpG Prognostic Risk Score Model Predicts Survival and Guides Therapy in Patients with Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer.Semantic proximity Read ↗

Prognostic value of partial EMT‐related genes in head and neck squamous cell carcinoma by a bioinformatic analysisSemantic proximity Read ↗

Phenotype remodelling of HNSCC cells in the muscle invasion environment.Semantic proximity Read ↗

Identification of a minimal biomarker profile in head-and-neck squamous cell carcinoma tumorsSemantic proximity Read ↗

A robust four CpGs-based prognostic risk score model predicts survival and guides therapy in patients with head and neck squamous cell carcinomaSemantic proximity Read ↗

Quantified pathway mutations associate epithelial-mesenchymal transition and immune escape with poor prognosis and immunotherapy resistance of head and neck squamous cell carcinoma.Semantic proximity Read ↗

Integrating Clinical and Genetic Analysis of Perineural Invasion in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Mesenchymal-epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expressionSemantic proximity Read ↗

Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.