Article
Quantified pathway mutations associate epithelial-mesenchymal transition and immune escape with poor prognosis and immunotherapy resistance of head and neck squamous cell carcinoma.
BMC medical genomics - 8 Feb 2024
Huang Yuhong, Liu Han, Liu Bo, Chen Xiaoyan, Li Danya, Xue Junyuan, Li Nan, Zhu Lei, Yang Liu, Xiao Jing, Liu Chao
Abstract excerpt
BACKGROUND: Pathway mutations have been calculated to predict the poor prognosis and immunotherapy resistance in head and neck squamous cell carcinoma (HNSCC). To uncover the unique markers predicting prognosis and immune therapy response, the accurate quantification of pathway mutations are required to evaluate epithelial-mesenchymal transition (EMT) and immune escape. Yet, there is a lack of score to accurately...
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