Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcriptional STAT3 is a potential target, whereas transcriptional STAT5A/5B/6 are new biomarkers for prognosis in human breast carcinoma.

Oncotarget - 30 May 2017

Wu Hua-Tao, Liu Jing, Li Guan-Wu, Shen Jia-Xin, Huang Yi-Teng

Abstract excerpt

Signal Transducer and Activators of Transcription (STAT) is a set of transcription factors, involved in diverse cellular functions. Evidences from cell lines, mouse models and human tissues implicate these transcription factors in the oncogenesis of breast cancer. However, the diverse expression patterns and prognostic values of 7 STATs remain to be elucidated. In the current study, we mined the transcriptional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Nucleic Acid
Share to Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Grading

Share to Neoplasm Staging

Share to STAT3 Transcription Factor

Share to STAT5 Transcription Factor

Share to STAT6 Transcription Factor

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 28422733
DOI: 10.18632/oncotarget.16748
PMCID: PMC5482654

Genes

STAT3
STAT1
STAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcriptional STAT3 is a potential target, whereas transcriptional STAT5A/5B/6 are new biomarkers for prognosis in human breast carcinoma.PMID 28422733Read ↗

Prognostic roles of signal transducers and activators of transcription family in human breast cancerSemantic proximity Read ↗

Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancerSemantic proximity Read ↗

A comprehensive analysis of the expression and prognosis of STATs in human breast invasive carcinomaSemantic proximity Read ↗

Roles and Regulation of Stat Family Transcription Factors in Human Breast CancerSemantic proximity Read ↗

The potential and controversy of targeting STAT family members in cancerSemantic proximity Read ↗

The prognostic values of signal transducers activators of transcription family in ovarian cancerSemantic proximity Read ↗

STAT3 genetic variant, alone and in combination with STAT5b polymorphism, contributes to breast cancer risk and clinical outcomes.Semantic proximity Read ↗

Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumorsSemantic proximity Read ↗

STAT3 Target Genes Relevant to Human CancersSemantic proximity Read ↗

STAT3 and STAT5b polymorphism contributes to breast cancer risk and clinical outcomes.Semantic proximity Read ↗

Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancerSemantic proximity Read ↗

STAT proteins as novel targets for cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.