Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell Transcriptomics Identifies a Unique Entity and Signature Markers of Transit-Amplifying Cells in Human Corneal Limbus

23 Jul 2021

Abstract excerpt

Purpose: Differentiated from adult stem cells (ASCs), transit-amplifying cells (TACs) play an important role in tissue homeostasis, development, and regeneration. This study aimed to characterize the gene expression profile of a candidate TAC population in limbal basal epithelial cells using single-cell RNA sequencing (scRNA-seq). Methods: Single cells isolated from the basal corneal limbus were subjected to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal surgery and disorders
Share to Corneal Surgery and Treatments
Share to Developmental Biology and Gene Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34297801
DOI: 10.1167/iovs.62.9.36

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell Transcriptomics Identifies a Unique Entity and Signature Markers of Transit-Amplifying Cells in Human Corneal LimbusPMID 34297801Read ↗

A single cell atlas of human cornea that defines its development, limbal stem and progenitor cells and the interactions with the limbal nicheSemantic proximity Read ↗

Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human corneaSemantic proximity Read ↗

Molecular characteristics and spatial distribution of adult human corneal cell subtypesSemantic proximity Read ↗

Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus MonkeysSemantic proximity Read ↗

Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stromaSemantic proximity Read ↗

A single cell transcriptome atlas reveals the heterogeneity of the healthy human cornea and identifies novel markers of the corneal limbus and stromaSemantic proximity Read ↗

Deciphering the heterogeneity of differentiating hPSC-derived corneal limbal stem cells through single-cell RNA-sequencingSemantic proximity Read ↗

Decoding murine corneal epithelial specification and homeostasis by single-cell spatial transcriptomics with scRNA-seq enrichmentSemantic proximity Read ↗

Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and diseaseSemantic proximity Read ↗

Single cell RNA-seq of human cornea organoids identifies cell fates of a developing immature corneaSemantic proximity Read ↗

Identification of the regulatory circuit governing corneal epithelial fate determination and diseaseSemantic proximity Read ↗

Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.