Article
Detection of mutations in NOD2/CARD15 gene in Arab patients with Crohn's disease.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Jan 2000
Siddique Iqbal, Mustafa Abu S, Khan Islam, Ziyab Ali H, Altarrah Munira, Sulaiman Riyas, Kadungothayil Numeer, Shaheed Faraz
Abstract excerpt
Background: Mutations in NOD2/CARD15 gene have been linked to an increased risk of Crohn's disease (CD). The objective of this study is to determine NOD2/CARD15 gene mutations, and their association with the risk of CD in Arabs in Kuwait. Methods: Four NOD2 gene mutations, including Pro268Ser (SNP5), Arg702Trp (SNP8), Gly908Arg (SNP12), and Leu1007FsinsC (SNP13) were examined in Arab CD patients (n = 103) and...
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