Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ENTPD3 Marks Mature Stem Cell–Derived β-Cells Formed by Self-Aggregation In Vitro

11 Aug 2021

Abstract excerpt

Stem cell-derived β-like cells (sBC) carry the promise of providing an abundant source of insulin-producing cells for use in cell replacement therapy for patients with diabetes, potentially allowing widespread implementation of a practical cure. To achieve their clinical promise, sBC need to function comparably with mature adult β-cells, but as yet they display varying degrees of maturity. Indeed, detailed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34380694
DOI: 10.2337/db20-0873

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ENTPD3 Marks Mature Stem Cell–Derived β-Cells Formed by Self-Aggregation In VitroPMID 34380694Read ↗

Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after TransplantationSemantic proximity Read ↗

Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2DSemantic proximity Read ↗

Kinetics and genomic profiling of adult human and mouse β-cell maturationSemantic proximity Read ↗

An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cellsSemantic proximity Read ↗

Comprehensive Characterization of Islet Remodeling in Development and in Diabetes Using Mass CytometrySemantic proximity Read ↗

Single-cell transcriptome profiling reveals β cell maturation in stem cell-derived islets after transplantationSemantic proximity Read ↗

Single-cell analyses of human islet cells reveal de-differentiation signaturesSemantic proximity Read ↗

DEC1 Regulates Human β Cell Functional Maturation and Circadian RhythmSemantic proximity Read ↗

Functional, metabolic and transcriptional maturation of stem cell derived beta cellsSemantic proximity Read ↗

Endocrine Pancreas Development and Dysfunction Through the Lens of Single-Cell RNA-SequencingSemantic proximity Read ↗

β-Cell Maturation and Identity in Health and Disease.Semantic proximity Read ↗

Advances Toward Engineering Functionally Mature Human Pluripotent Stem Cell-Derived β CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.