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Article

No Tumor Suppressor Role for LKB1 in Prostate Cancer.

DNA and cell biology - 1 Sept 2021

Koseoglu Hikmet, Celebi Asuman, Galamiyeva Gunay, Dalay Nejat, Ozkardes Hakan, Buyru Nur

Abstract excerpt

To elucidate the pathogenesis of prostate diseases, following in silico analysis, the LKB1 gene was selected for further investigation. The LKB1 gene has been associated with poor prognosis and is frequently mutated in different types of cancers. In this study, 50 benign prostatic hyperplasia (BPH) and 57 prostate cancer (PCa) tissues, including matched normal tissue for the patients, were analyzed by qRT-PCR and...

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Identifiers

PMID: 34370601
DOI: 10.1089/dna.2021.0274

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