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Article

A functional insertion/deletion polymorphism in the promoter region of the NFKB1 gene increases susceptibility for prostate cancer.

Cancer genetics and cytogenetics - 1 Jun 2009

Zhang Peng, Wei Qiang, Li Xiang, Wang Kunjie, Zeng Hao, Bu Hong, Li Hong

Abstract excerpt

Among men, cancers of the prostate, lung and bronchus, and colon and rectum account for about 50% of all newly diagnosed cancers, and prostate cancer alone accounts for about 25% of incident cases. Nuclear factor-kappaB (NF-kappaB)-activation plays a critical role in prostate cancer by NF-kappaB inhibitor kinase beta pathway-mediated inflammatory-induced tumorigenesis. A functional insertion/deletion polymorphism...

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Identifiers

PMID: 19446741
DOI: 10.1016/j.cancergencyto.2009.01.017

Genes

NFKB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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