Article
Associations of CYLD, JAK2 and TLR4 Genotypes with PSA Levels and Immunophenotype in Benign Prostatic Hyperplasia and Prostate Cancer.
Frontiers in bioscience (Landmark edition) - 19 Jul 2024
Duy Le Vu, Huong Pham Thi, Nam Nguyen Trung, Trang Do Thi, Chau Nghiem Thi Minh, Thao Tran Thi Phuong, Hoang Nguyen Huy, Tao Nguyen Thien, Mao Can Van, Xuan Nguyen Thi
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) is one of the most common malignant tumors of the male urinary system, and its incidence and mortality rates have been increasing worldwide. Benign prostatic hyperplasia (BPH) represents stromal and epithelial cell proliferation in the prostate in elderly males. Abnormal activation of inflammation-related signalling molecules, such as toll-like receptor 4 (TLR4) and Janus...
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