Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of Metabolite Levels on Type 2 Diabetes Mellitus and Glycemic Traits: A Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 19 Nov 2021

Sun Yue, Lu Ya-Ke, Gao Hao-Yu, Yan Yu-Xiang

Abstract excerpt

OBJECTIVE: To assess the causal associations of plasma levels of metabolites with type 2 diabetes mellitus (T2DM) and glycemic traits. METHODS: Two-sample mendelian randomization (MR) was conducted to assess the causal associations. Genetic variants strongly associated with metabolites at genome-wide significance level (P < 5 × 10-8) were selected from public genome-wide association studies, and single-nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Blood Glucose
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Glycated Hemoglobin

Share to Insulin

Share to Mendelian Randomization Analysis

Share to Metabolome

Source

Identifiers

PMID: 34363473
DOI: 10.1210/clinem/dgab581

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of Metabolite Levels on Type 2 Diabetes Mellitus and Glycemic Traits: A Mendelian Randomization Study.PMID 34363473Read ↗

A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes.Semantic proximity Read ↗

Association of genetic variants related to plasma fatty acids with type 2 diabetes mellitus and glycaemic traits: a Mendelian randomisation study.Semantic proximity Read ↗

The causal relationship between human blood metabolites and the risk of visceral obesity: a mendelian randomization analysisSemantic proximity Read ↗

Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challengesSemantic proximity Read ↗

Type 2 Diabetes and Adiposity Induce Different Lipid Profile Disorders: A Mendelian Randomization Analysis.Semantic proximity Read ↗

Investigation of the Causal Association between Long-Chain n-6 Polyunsaturated Fatty Acid Synthesis and the Risk of Type 2 Diabetes: A Mendelian Randomization Analysis.Semantic proximity Read ↗

Mendelian Randomization Study on Serum Metabolites and Diabetic Nephropathy Risk: Identifying Potential Biomarkers for Early Intervention.Semantic proximity Read ↗

Causal relationship between plasma metabolites and hypertension: A Mendelian randomization study.Semantic proximity Read ↗

Causal Association of Type 2 Diabetes Mellitus and Glycemic Traits With Cardiovascular Diseases and Lipid Traits: A Mendelian Randomization Study.Semantic proximity Read ↗

Blood lipid profile, HbA1c, fasting glucose, and diabetes: a cohort study and a two-sample Mendelian randomization analysis.Semantic proximity Read ↗

Causal association of genetically predicted 1400 blood metabolites with inflammatory bowel disease risk: A Mendelian randomization study.Semantic proximity Read ↗

Causality of genetically determined blood metabolites on inflammatory bowel disease: a two-sample Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.