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Article

Lifetime risk of rheumatoid arthritis-associated interstitial lung disease in MUC5B mutation carriers.

Annals of the rheumatic diseases - 1 Dec 2021

Palomäki Antti, Palotie Aarno, Koskela Jukka, Eklund Kari K, Pirinen Matti, Ripatti Samuli, Laitinen Tarja, Mars Nina

Abstract excerpt

OBJECTIVES: To estimate lifetime risk of developing rheumatoid arthritis-associated interstitial lung disease (RA-ILD) with respect to the strongest known risk factor for pulmonary fibrosis, a MUC5B promoter variant. METHODS: FinnGen is a collection of epidemiological cohorts and hospital biobank samples, integrating genetic data with up to 50 years of follow-up within nationwide registries in Finland. Patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34344703
DOI: 10.1136/annrheumdis-2021-220698
PMCID: PMC8600604

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