Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Oncologic Safety of Prophylactic Nipple-Sparing Mastectomy in a Population With BRCA Mutations: A Multi-institutional Study.

JAMA surgery - 1 Feb 2018

Jakub James W, Peled Anne Warren, Gray Richard J, Greenup Rachel A, Kiluk John V, Sacchini Virgilio, McLaughlin Sarah A, Tchou Julia C, Vierkant Robert A, Degnim Amy C, Willey Shawna

Abstract excerpt

Importance: Nipple-sparing mastectomy (NSM) offers superior cosmetic outcomes and has been gaining wide acceptance; however, its role among patients with BRCA mutations remains controversial. Objective: To report on the oncologic safety of NSM and provide evidence-based data to patients and health care professionals regarding preservation of the nipple-areolar complex during a risk-reducing mastectomy in a...

Topics

Adult
Female
Follow-Up Studies
Genes, BRCA1
Genes, BRCA2
Humans
Middle Aged
Mutation
Neoplasms, Second Primary
Nipples
Organ Sparing Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prophylactic Mastectomy

Retrospective Studies

Unilateral Breast Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28903167
DOI: 10.1001/jamasurg.2017.3422
PMCID: PMC5838709

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncologic Safety of Prophylactic Nipple-Sparing Mastectomy in a Population With BRCA Mutations: A Multi-institutional Study.PMID 28903167Read ↗

How Protective are Nipple-Sparing Prophylactic Mastectomies in BRCA1 and BRCA2 Mutation Carriers?Semantic proximity Read ↗

Bilateral Prophylactic Nipple-Sparing Mastectomy: Analysis of the Risk-Reducing Effect in BRCA1/2 Mutation Carriers.Semantic proximity Read ↗

Use of bilateral prophylactic nipple-sparing mastectomy in patients with high risk of breast cancer.Semantic proximity Read ↗

Low rate of complications in nipple-sparing mastectomy for patients with BRCA1 and BRCA2 mutation.Semantic proximity Read ↗

Oncologic Safety of Nipple-Sparing Mastectomy for Breast Cancer in BRCA Gene Mutation Carriers: Outcomes at 70 Months Median Follow-Up.Semantic proximity Read ↗

Nipple-sparing mastectomy in patients with BRCA1/2 mutations and variants of uncertain significance.Semantic proximity Read ↗

Nipple Sparing Mastectomy as a Risk-Reducing Procedure for BRCA-Mutated Patients.Semantic proximity Read ↗

Total skin-sparing mastectomy in BRCA mutation carriers.Semantic proximity Read ↗

Nipple-sparing mastectomy in BRCA1/2 mutation carriers: an interim analysis and review of the literature.Semantic proximity Read ↗

Oncological safety and preventive impact of nipple-sparing mastectomy in patients with BRCA1/2 mutation: multicentre study of the Korea Robot-endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG).Semantic proximity Read ↗

Feasibility study of contralateral risk-reducing mastectomy with breast reconstruction for breast cancer patients with BRCA mutations in Japan.Semantic proximity Read ↗

Prophylactic mastectomies in patients with breast cancer and known germline pathogenetic variants: an Austrian registrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.