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Article

Novel neutrophil phenotypic signature in pediatric patients with type 1 diabetes and diabetic ketoacidosis.

Journal of leukocyte biology - 1 Apr 2022

Nichols Blake E, Hook Jessica S, Weng Kayson, Ahn Chul, Moreland Jessica G

Abstract excerpt

Type 1 diabetes (T1D) is a chronic inflammatory condition sometimes complicated by acute diabetic ketoacidosis (DKA). A subset of patients with T1D develop DKA independent of known risk factors. This study tested the hypothesis that circulating polymorphonuclear leukocytes (PMN) from children with T1D and DKA would exhibit a primed phenotype and that the signature would be unique in patients predisposed to have...

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PMID: 34342036
DOI: 10.1002/JLB.3A1220-826R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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