EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer.

doi:10.1158/1940-6207.CAPR-21-0161

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Article

EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer.

Cancer prevention research (Philadelphia, Pa.) - 1 Nov 2021

Katona Bryson W, Long Jessica M, Ahmad Nuzhat A, Attalla Sara, Bradbury Angela R, Carpenter Erica L, Clark Dana F, Constantino Gillain, Das Koushik K, Domchek Susan M, Dudzik Christina, Ebrahimzadeh Jessica, Ginsberg Gregory G, Heiman Jordan, Kochman Michael L, Maxwell Kara N, McKenna Danielle B, Powers Jacquelyn, Shah Payal D, Wangensteen Kirk J, Rustgi Anil K

Abstract excerpt

Carriers of a pathogenic/likely pathogenic (P/LP) BRCA1/BRCA2/ATM/PALB2 variant are at increased risk of pancreatic ductal adenocarcinoma (PDAC), yet current guidelines recommend surveillance only for those with a family history of PDAC. We aimed to investigate outcomes of endoscopic ultrasound (EUS)-based PDAC surveillance in BRCA1/BRCA2/ATM/PALB2 carriers without a family history of PDAC. We performed a...

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PMID: 34341011
DOI: 10.1158/1940-6207.CAPR-21-0161
PMCID: PMC8563408

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