Article
Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.
Journal of the American College of Surgeons - 1 Jan 2020
Cao Carrie X, Sharib Jeremy M, Blanco Amie M, Goldberg Dena, Bracci Paige, Mukhtar Rita A, Esserman Laura J, Kirkwood Kimberly S
Abstract excerpt
BACKGROUND: Direct-to-consumer BRCA testing will increase BRCA diagnoses and subsequent abdominal imaging. It is unclear whether BRCA carriers are at higher risk of developing pancreatic cysts (PCs) or cyst-associated pancreatic ductal adenocarcinoma (PDAC). We investigated the prevalence of PCs in BRCA-tested patients, and whether BRCA-carriers have higher rates of PDAC when PCs are found. STUDY DESIGN: This is...
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