Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review

19 Apr 2019

Abstract excerpt

Acinar cell carcinoma (ACC) is a rare pancreatic neoplasm with dismal prognosis. Insights into the molecular basis of ACC can pave the way for the application of more effective, personalized therapies and detection of patients with hereditary predisposition.Molecular analysis revealed a germline BRCA2 (and CHEK2) mutation in a patient with a rare pancreatic ACC with extensive intraductal growth. Somatic loss of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Neuroendocrine Tumor Research Advances
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31002019
DOI: 10.1080/15384047.2019.1595274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature reviewPMID 31002019Read ↗

Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma.Semantic proximity Read ↗

Exceptional Response of Pancreatic Acinar Cell Carcinoma and Bile Duct Cancer to Platinum-Based Chemotherapy in a Family With a Germline BRCA2 Variant.Semantic proximity Read ↗

BRCA-mutant pancreatic ductal adenocarcinoma.Semantic proximity Read ↗

Hereditary pancreatic cancer.Semantic proximity Read ↗

Molecular and Clinical Features of Pancreatic Acinar Cell Carcinoma: A Single Institution Case SeriesSemantic proximity Read ↗

Treatment opportunities and future perspectives for pancreatic cancer patients with germline BRCA1-2 pathogenic variantsSemantic proximity Read ↗

Identification of germline genetic mutations in patients with pancreatic cancerSemantic proximity Read ↗

The role of germline BRCA1 & BRCA2 mutations in familial pancreatic cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

Genomic Features and Clinical Management of Patients with Hereditary Pancreatic Cancer Syndromes and Familial Pancreatic CancerSemantic proximity Read ↗

Germline Pathogenic Variants in Patients with Pancreatic Ductal Adenocarcinoma and Extra-Pancreatic Malignancies: A Nationwide Database AnalysisSemantic proximity Read ↗

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.Semantic proximity Read ↗

[Pancreatic acinar cell carcinoma: Clinical and theranostic characteristics].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.