Article
Cluster Analysis and Genotype-Phenotype Assessment of Geographic Atrophy in Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report 25.
Ophthalmology. Retina - 1 Nov 2021
Keenan Tiarnan D L, Oden Neal L, Agrón Elvira, Clemons Traci E, Henning Alice, Fritsche Lars G, Wong Wai T, Chew Emily Y
Abstract excerpt
PURPOSE: To explore whether phenotypes in geographic atrophy (GA) secondary to age-related macular degeneration can be separated into 2 or more partially distinct subtypes and if these have different genetic associations. This is important because distinct GA subtypes associated with different genetic factors might require customized therapeutic approaches. DESIGN: Cluster analysis of participants within a...
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