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Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration: The EYE-RISK Consortium.

Ophthalmology. Retina - 1 Dec 2020

Biarnés Marc, Colijn Johanna M, Sousa Jose, Ferraro Lucia L, Garcia Míriam, Verzijden Timo, Meester-Smoor Magda A, Delcourt Cécile, Klaver Caroline C W, den Hollander Anneke I, Lengyel Imre, Peto Tunde, Monés Jordi

Abstract excerpt

PURPOSE: Geographic atrophy (GA) secondary to age-related macular degeneration is considered a single entity. This study aimed to determine whether GA subgroups exist that can be defined by their genotype and phenotype. DESIGN: Retrospective analysis of cross-sectional data. PARTICIPANTS: Individuals (196 eyes of 196 patients) 50 years of age or older with GA from the EYE-RISK database. METHODS: Participants were...

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PMID: 32371126
DOI: 10.1016/j.oret.2020.04.014

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