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Article

Assessing the role of cortisol in cancer: a wide-ranged Mendelian randomisation study.

British journal of cancer - 1 Sept 2021

Larsson Susanna C, Lee Wei-Hsuan, Kar Siddhartha, Burgess Stephen, Allara Elias

Abstract excerpt

BACKGROUND: Cortisol's immunosuppressive, obesogenic, and hyperglycaemic effects suggest that it may play a role in cancer development. However, whether cortisol increases cancer risk is not known. We investigated the potential causal association between plasma cortisol and risk of overall and common site-specific cancers using Mendelian randomisation. METHODS: Three genetic variants associated with morning...

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Identifiers

PMID: 34316022
DOI: 10.1038/s41416-021-01505-8
PMCID: PMC8476513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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