Article
Normal-sized basal ganglia perivascular space related to motor phenotype in Parkinson freezers.
Aging - 27 Jul 2021
Lv Wen, Yue Yumei, Shen Ting, Hu Xingyue, Chen Lili, Xie Fei, Zhang Wenying, Zhang Baorong, Gui Yaxing, Lai Hsin-Yi, Ba Fang
Abstract excerpt
Changes in basal ganglia (BG) perivascular spaces (PVSs) are related to motor and cognitive behaviors in Parkinson's disease (PD). However, the correlation between the initial motor phenotype and PVSs distribution/burden in PD freezing of gait (FOG) remains unclear. In addition, the normal-sized PVSs (nPVSs) have not been well-studied. With high-resolution 7T-MRI, we studied nPVSs burden in BG, thalamus, midbrain...
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