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Article

Regional homogeneity alterations differentiate between tremor dominant and postural instability gait difficulty subtypes of Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2016

Jiang Siming, Wang Min, Zhang Li, Yuan Yongsheng, Tong Qing, Ding Jian, Wang Jianwei, Xu Qinrong, Zhang Kezhong

Abstract excerpt

Parkinson's disease (PD) can be classified into the tremor dominant (TD) subtype and the postural instability gait difficulty (PIGD) subtype, which present with different clinical courses and prognoses. However, the symptom-specific intrinsic neural mechanisms underlying the subtypes of PD still remain elusive. In the current study, we utilized resting-state fMRI (rs-fMRI) combined with the regional homogeneity...

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Source

Identifiers

PMID: 26666253
DOI: 10.1007/s00702-015-1490-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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