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Article

Family based and case-control designs reveal an association of TFAP2A in nonsyndromic cleft lip only among Vietnamese population.

Molecular genetics & genomic medicine - 1 Sept 2021

Nguyen Duc Minh, Suzuki Satoshi, Imura Hideto, Niimi Teruyuki, Furukawa Hiroo, Ta Thanh-Van, Tong Son Minh, Nguyen Tra Thu, Pham Loc Nguyen Gia, Tran Duy Le, Natsume Nagato

Abstract excerpt

AIMS: Dozens of causative genes and their mechanisms of nonsyndromic cleft lip with or without cleft palate (NSCL/P) were revealed through genome-wide association and linkage studies. Results were, however, not always replicated in different populations or methodologies. This study used case-control and family based approaches to investigate the etiology of NSCL/P and its two subtypes: nonsyndromic cleft lip only...

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Identifiers

PMID: 34310873
DOI: 10.1002/mgg3.1754
PMCID: PMC8457689

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