Article
Case-control and family-based association studies of novel susceptibility locus 8q24 in nonsyndromic cleft lip with or without cleft palate in a Southern Han Chinese population located in Guangdong Province.
DNA and cell biology - 1 May 2012
Xu Ming Yan, Deng Xiao Ling, Tata Laila Jal, Han Hui, Chen Xi He, Liu Ting Ying, Chen Qing Shan, Yao Xiao Wu, Tang Shi Jie
Abstract excerpt
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common congenital malformations and a susceptibility locus on chromosome 8q24 has been replicated as a genetic risk factor for NSCL/P in patients of European and Asian descent. However, given considerable variations in allele frequencies across geographical regions studied, the aim of this study was to investigate the association of...
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